17.2.14, Cas9: The Enzyme, The RNA & The Virus
Great minds from the Eric Greene Lab (Columbia University) and the Jennifer Doudna Lab (University of California) have released an educational video describing how Cas9 searches DNA for target sites:
Cas9: The Enzyme, The RNA & The Virus
We strongly recommend you follow the link and watch this video! And if you got interested, check out the newly published paper on which the used structures are based on:
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 by Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA; Nature 2014 Jan.29